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Calcium Disodium EDTA vs Cyclopentasiloxane: which is worse?

Quick answer: Both score equally on our risk model. Calcium Disodium EDTA is in the EU and in the US; Cyclopentasiloxane is restricted in the EU and allowed in the US.

PropertyCalcium Disodium EDTACyclopentasiloxane
EU statusRestricted
US statusAllowed
Risk levelmedium
Banned in
Restricted inEuropean Union (restricted to specific food categories; not approved for many applications permitted in US)European Union
Categoryadditiveendocrine disruptor
Where it hideshair serum, primer, deodorant

What is Calcium Disodium EDTA?

Calcium disodium EDTA (ethylenediaminetetraacetate) is a chelating agent used as a food preservative. It binds metal ions (particularly iron and copper) that would otherwise catalyze oxidative and color-degradation reactions in foods. It prevents color loss, flavor changes, and bacterial growth in certain foods.

What is Cyclopentasiloxane?

Cyclopentasiloxane is a volatile silicone (D5) used for smooth, silky texture.

Documented risks

Calcium Disodium EDTA: EDTA chelates essential minerals including zinc, iron, calcium, and magnesium in the gut, potentially reducing absorption of these nutrients with regular consumption. Animal studies at high doses show reproductive toxicity and zinc deficiency effects. EFSA's safety assessment noted that EDTA could reduce zinc bioavailability at consumption levels that could be reached by high consumers of EDTA-containing foods. The ADI is 1.9 mg/kg body weight. EDTA's poor biodegradability also makes it an environmental concern — it accumulates in water supplies and can mobilize heavy metals in sediments.

Cyclopentasiloxane: Persistent and bioaccumulative; the EU restricts D5 in wash-off products over environmental and endocrine concerns. The US has no restriction.

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