Calcium Disodium EDTA vs Homosalate: which is worse?
Quick answer: Both score equally on our risk model. Calcium Disodium EDTA is — in the EU and — in the US; Homosalate is restricted in the EU and allowed in the US.
| Property | Calcium Disodium EDTA | Homosalate |
|---|---|---|
| EU status | — | Restricted |
| US status | — | Allowed |
| Risk level | — | medium |
| Banned in | — | — |
| Restricted in | European Union (restricted to specific food categories; not approved for many applications permitted in US) | European Union |
| Category | additive | uv filter |
| Where it hides | — | sunscreen, SPF moisturizer, SPF foundation |
What is Calcium Disodium EDTA?
Calcium disodium EDTA (ethylenediaminetetraacetate) is a chelating agent used as a food preservative. It binds metal ions (particularly iron and copper) that would otherwise catalyze oxidative and color-degradation reactions in foods. It prevents color loss, flavor changes, and bacterial growth in certain foods.
What is Homosalate?
Homosalate is an organic UV filter that absorbs UVB radiation.
Documented risks
Calcium Disodium EDTA: EDTA chelates essential minerals including zinc, iron, calcium, and magnesium in the gut, potentially reducing absorption of these nutrients with regular consumption. Animal studies at high doses show reproductive toxicity and zinc deficiency effects. EFSA's safety assessment noted that EDTA could reduce zinc bioavailability at consumption levels that could be reached by high consumers of EDTA-containing foods. The ADI is 1.9 mg/kg body weight. EDTA's poor biodegradability also makes it an environmental concern — it accumulates in water supplies and can mobilize heavy metals in sediments.
Homosalate: A suspected endocrine disruptor; the EU limits it to 7.34% in face products (2025), well below typical US concentrations.
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