Erythritol vs Corn Syrup Solids: which is worse?

What is Erythritol?

Erythritol is a four-carbon sugar alcohol naturally occurring in small amounts in fruits, fermented foods, and mushrooms. Commercially produced via fermentation of glucose by yeasts such as Moniliella pollinis, it has approximately 70% of sucrose's sweetness, provides 0.24 kcal/g, and has a glycemic index of 0. It is nearly completely absorbed in the small intestine and excreted unchanged in urine, which explains its unusually low laxative effect compared to other polyols.

What is Corn Syrup Solids?

Corn syrup solids are produced by drying corn syrup to a moisture content below 10%, yielding a free-flowing powder. They are composed of a mixture of glucose polymers (polysaccharides) and monosaccharides derived from corn starch hydrolysis. Unlike liquid corn syrup, they are used in powdered products such as non-dairy creamers, infant formula, and seasoning blends.

Documented risks

Erythritol: A 2023 observational study published in Nature Medicine (Hazen et al., Cleveland Clinic) found that elevated blood erythritol levels were associated with increased risk of major adverse cardiovascular events (MACE), including heart attack and stroke. Additionally, erythritol was found to enhance platelet aggregation in vitro. This study was widely reported and has generated significant scientific debate; critics note that it was observational (not causational), and that the study population had pre-existing cardiovascular risk factors. Regulatory agencies have not changed their approval status. The long-term cardiovascular implications require further research.

Corn Syrup Solids: Corn syrup solids contribute to added sugar intake and share the metabolic risks of high-sugar diets, including increased risk of obesity, type 2 diabetes, and dental caries. Their presence in infant formula has raised particular concern among pediatric nutritionists, as they have a high glycemic index and provide no nutritional benefit beyond calories. The American Academy of Pediatrics recommends limiting added sugars for all age groups, including infants. Regulatory agencies have not specifically restricted corn syrup solids.