Invert Sugar vs Allulose: which is worse?

What is Invert Sugar?

Invert sugar is a mixture of equal parts glucose and fructose produced by the acid or enzymatic hydrolysis of sucrose. It is sweeter than table sugar by about 25% and has enhanced moisture-retaining properties. Bees naturally produce invert sugar in honey through the enzyme invertase.

What is Allulose?

Allulose (D-psicose) is a rare sugar monosaccharide naturally present in trace amounts in wheat, figs, raisins, and jackfruit. It has about 70% of sucrose's sweetness but provides only 0.4 kcal/g (about 10% of sucrose's calories) because it is absorbed but not metabolized. The FDA exempted allulose from the 'total sugars' declaration in 2019.

Documented risks

Invert Sugar: Invert sugar poses the same metabolic risks as other added sugars. The free fructose component is metabolized directly in the liver, and excessive fructose consumption has been linked to non-alcoholic fatty liver disease, increased triglycerides, and insulin resistance, as documented in multiple reviews including a 2013 paper in Current Opinion in Lipidology. At moderate consumption, it is not specifically more harmful than sucrose. Regulatory agencies worldwide permit its use without restriction.

Allulose: Generally considered safe with a favorable glycemic profile. Human studies show that allulose does not raise blood glucose or insulin. GI effects (bloating, abdominal cramping, diarrhea) have been reported in dose-response studies above 0.4 g/kg body weight; a 2016 study in the journal Food & Chemical Toxicology established a no-observed-adverse-effect level (NOAEL) in humans. Compared to erythritol, no cardiovascular concerns have been raised in the literature.