Maltodextrin vs Monk Fruit Extract: which is worse?

What is Maltodextrin?

Maltodextrin is a polysaccharide derived by partial hydrolysis of starch — most commonly corn starch in the US, but also wheat, potato, or rice starch. It is a white powder with a mild, slightly sweet taste and is highly soluble. Despite being classified as a carbohydrate, maltodextrin has a high glycemic index (GI of 85–105), often higher than table sugar.

What is Monk Fruit Extract?

Monk fruit extract is derived from the fruit of Siraitia grosvenorii, a melon native to southern China. Its sweetness (150–250 times that of sucrose) comes from mogrosides, particularly mogroside V, rather than simple sugars. It has been used in traditional Chinese medicine for centuries. The FDA granted GRAS status in 2010.

Documented risks

Maltodextrin: Maltodextrin's very high glycemic index (GI 85–105) means it causes rapid blood glucose spikes, potentially problematic for people with diabetes or insulin resistance. A 2012 study in PLoS ONE (Bhatt et al.) found that maltodextrin suppressed beneficial gut bacteria (like Lactobacillus) and increased Escherichia coli biofilm formation associated with Crohn's disease. A 2022 study in Nutrients noted maltodextrin's potential to disrupt gut microbiome composition at typical dietary intakes. Regulatory agencies have not restricted its use, but nutrition researchers increasingly flag it as a low-quality carbohydrate.

Monk Fruit Extract: Currently considered safe with no significant adverse effects reported in human studies. Animal studies have shown mogrosides to have antioxidant, anti-inflammatory, and possible anti-diabetic properties. No carcinogenicity, mutagenicity, or reproductive toxicity has been identified. Due to its relatively recent introduction as a food additive in Western markets, long-term human safety data are more limited compared to older sweeteners. Overall, the safety profile is favorable.