Maltodextrin vs Sodium Propionate: which is worse?

What is Maltodextrin?

Maltodextrin is a polysaccharide derived by partial hydrolysis of starch — most commonly corn starch in the US, but also wheat, potato, or rice starch. It is a white powder with a mild, slightly sweet taste and is highly soluble. Despite being classified as a carbohydrate, maltodextrin has a high glycemic index (GI of 85–105), often higher than table sugar.

What is Sodium Propionate?

Sodium propionate is the sodium salt of propionic acid. Like calcium propionate (E282), it is used as an antimicrobial preservative to prevent mold and bacterial spoilage in bread and baked goods. It is also used in poultry and animal feed applications.

Documented risks

Maltodextrin: Maltodextrin's very high glycemic index (GI 85–105) means it causes rapid blood glucose spikes, potentially problematic for people with diabetes or insulin resistance. A 2012 study in PLoS ONE (Bhatt et al.) found that maltodextrin suppressed beneficial gut bacteria (like Lactobacillus) and increased Escherichia coli biofilm formation associated with Crohn's disease. A 2022 study in Nutrients noted maltodextrin's potential to disrupt gut microbiome composition at typical dietary intakes. Regulatory agencies have not restricted its use, but nutrition researchers increasingly flag it as a low-quality carbohydrate.

Sodium Propionate: The health profile is essentially the same as calcium propionate. The 2019 Science Translational Medicine study implicating propionate in metabolic changes applies to all propionate salts. Behavioral sensitivity concerns that have been anecdotally reported with calcium propionate may similarly apply. At regulated use levels, sodium propionate is considered safe by global regulatory agencies.