Silicon Dioxide vs Erythritol: which is worse?

What is Silicon Dioxide?

Silicon dioxide (silica) is a naturally occurring mineral compound used as an anti-caking agent in powdered and granular foods. The food-grade form is amorphous (non-crystalline) synthetic silica, distinct from the crystalline quartz form associated with lung disease. It absorbs moisture and prevents clumping in powders.

What is Erythritol?

Erythritol is a four-carbon sugar alcohol naturally occurring in small amounts in fruits, fermented foods, and mushrooms. Commercially produced via fermentation of glucose by yeasts such as Moniliella pollinis, it has approximately 70% of sucrose's sweetness, provides 0.24 kcal/g, and has a glycemic index of 0. It is nearly completely absorbed in the small intestine and excreted unchanged in urine, which explains its unusually low laxative effect compared to other polyols.

Documented risks

Silicon Dioxide: Food-grade amorphous silicon dioxide is generally recognized as safe. EFSA re-evaluated it in 2018 and concluded there was no safety concern at typical dietary exposure levels; however, the panel noted uncertainty about nanoparticle forms. The food form should not be confused with crystalline silica (quartz) dust, which is a recognized carcinogen when inhaled occupationally. Ingested amorphous silica passes through the body largely unabsorbed.

Erythritol: A 2023 observational study published in Nature Medicine (Hazen et al., Cleveland Clinic) found that elevated blood erythritol levels were associated with increased risk of major adverse cardiovascular events (MACE), including heart attack and stroke. Additionally, erythritol was found to enhance platelet aggregation in vitro. This study was widely reported and has generated significant scientific debate; critics note that it was observational (not causational), and that the study population had pre-existing cardiovascular risk factors. Regulatory agencies have not changed their approval status. The long-term cardiovascular implications require further research.