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Triclosan vs Perfluorinated Compounds (PFAS): which is worse?

Quick answer: Triclosan carries the heavier risk profile. Triclosan is restricted in the EU and allowed in the US; Perfluorinated Compounds (PFAS) is in the EU and in the US.

PropertyTriclosanPerfluorinated Compounds (PFAS)
EU statusRestricted
US statusAllowed
Risk levelhigh
Banned inEuropean Union (broadly restricting PFAS in food contact materials since 2020; EU-wide PFAS restriction proposal under REACH), Denmark (banned PFAS in all food packaging 2020)
Restricted inEuropean UnionUnited States (EPA has set maximum contaminant levels for 6 PFAS in drinking water in 2024; FDA has been working with industry to phase out certain PFAS from food packaging)
Categoryendocrine disruptoradditive
Where it hidesantibacterial soap, toothpaste, deodorant

What is Triclosan?

Triclosan is an antibacterial and antifungal agent.

What is Perfluorinated Compounds (PFAS)?

Per- and polyfluoroalkyl substances (PFAS) are a large family of synthetic chemicals characterized by extremely strong carbon-fluorine bonds. They are used in food packaging (grease-resistant coatings), non-stick cookware (PTFE/Teflon), food processing equipment, firefighting foam, and many industrial applications. The 'forever chemicals' moniker reflects their extreme environmental persistence.

Documented risks

Triclosan: An endocrine disruptor linked to antibiotic resistance. Restricted in the EU and banned in US over-the-counter antibacterial soaps, but still allowed in some products.

Perfluorinated Compounds (PFAS): PFAS are among the most extensively studied and harmful groups of synthetic chemicals in the modern environment. Their unique carbon-fluorine bond stability means they do not break down in the environment or in human body tissues — contributing to bioaccumulation over a lifetime. Health effects documented in human epidemiological studies include: - Cancer: PFOA (perfluorooctanoic acid) and PFOS (perfluorooctanesulfonic acid) have been associated with kidney cancer, testicular cancer, thyroid cancer, bladder cancer, and non-Hodgkin lymphoma in occupationally exposed workers and community members with contaminated drinking water. IARC classified PFOA as Group 1 (human carcinogen) in 2023 and PFOS as Group 2B. - Endocrine disruption: PFAS disrupt thyroid hormone signaling and sex hormone balance. Multiple studies find associations between PFAS exposure and hypothyroidism, early puberty in girls, and reduced sperm quality. - Immune suppression: studies have found that PFAS exposure is associated with reduced vaccine response in children and adults, suggesting PFAS may impair immune function. - Developmental effects: prenatal PFAS exposure has been associated with lower birth weight, developmental delays, and reduced immune response in infants. - Cholesterol: PFAS exposure consistently raises LDL cholesterol levels, increasing cardiovascular disease risk. The 2023 EPA MCLG (maximum contaminant level goal) for PFOA and PFOS is zero — reflecting the agency's conclusion that there is no safe level. The EPA set enforceable MCLs in drinking water in 2024. The DuPont/3M PFOA/PFOS contamination of drinking water in communities near Teflon manufacturing facilities led to a $671 million settlement (DuPont/Chemours, 2017) and $10.3 billion 3M settlement (2023) — among the largest environmental contamination settlements in history.

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