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Allulose vs Sorbitol: which is worse?

Quick answer: Allulose carries the heavier risk profile. Allulose is restricted in the EU and allowed in the US; Sorbitol is allowed in the EU and allowed in the US.

PropertyAlluloseSorbitol
EU statusRestrictedAllowed
US statusAllowedAllowed
Risk levellowlow
Banned in
Restricted inEU (novel food status, limited approval)
Categoryadditiveadditive
Where it hidesAtkins products, Quest Low Carb, Enlightened Ice CreamOrbit Gum, Werther's Sugar Free, Russell Stover Sugar Free

What is Allulose?

Allulose (D-psicose) is a rare sugar monosaccharide naturally present in trace amounts in wheat, figs, raisins, and jackfruit. It has about 70% of sucrose's sweetness but provides only 0.4 kcal/g (about 10% of sucrose's calories) because it is absorbed but not metabolized. The FDA exempted allulose from the 'total sugars' declaration in 2019.

What is Sorbitol?

Sorbitol is a sugar alcohol (polyol) naturally found in some fruits, including apples, pears, and prunes. Commercially, it is produced by hydrogenation of glucose. It has approximately 60% of the sweetness of sucrose but provides fewer calories (2.6 kcal/g vs 4 kcal/g for sugar) and does not cause a significant immediate insulin response.

Documented risks

Allulose: Generally considered safe with a favorable glycemic profile. Human studies show that allulose does not raise blood glucose or insulin. GI effects (bloating, abdominal cramping, diarrhea) have been reported in dose-response studies above 0.4 g/kg body weight; a 2016 study in the journal Food & Chemical Toxicology established a no-observed-adverse-effect level (NOAEL) in humans. Compared to erythritol, no cardiovascular concerns have been raised in the literature.

Sorbitol: At doses above 20–50 g/day, sorbitol can cause osmotic diarrhea because it is incompletely absorbed in the small intestine and is fermented by colonic bacteria. EU regulations require products containing more than 10% added polyols to carry the label 'excessive consumption may produce laxative effects.' This is well-known and predictable. Sorbitol is not carcinogenic and does not raise blood glucose significantly, making it suitable for diabetics in controlled amounts.

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