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Homosalate vs Sulfur Dioxide: which is worse?

Quick answer: Sulfur Dioxide carries the heavier risk profile. Homosalate is restricted in the EU and allowed in the US; Sulfur Dioxide is in the EU and in the US.

PropertyHomosalateSulfur Dioxide
EU statusRestricted
US statusAllowed
Risk levelmedium
Banned in
Restricted inEuropean UnionEuropean Union (ADI 0.7 mg/kg body weight; mandatory 'contains sulfites' labeling in wine and food), United States (banned from fresh produce 1986; mandatory labeling above 10 ppm)
Categoryuv filteradditive
Where it hidessunscreen, SPF moisturizer, SPF foundation

What is Homosalate?

Homosalate is an organic UV filter that absorbs UVB radiation.

What is Sulfur Dioxide?

Sulfur dioxide (SO2) is a colorless gas used as a food preservative and antioxidant. It is the primary active form of the sulfite family of food additives. It is generated by burning sulfur or as a byproduct of certain chemical processes. In food use, it is released from various sulfite salts (E221-E228) and directly applied to some foods.

Documented risks

Homosalate: A suspected endocrine disruptor; the EU limits it to 7.34% in face products (2025), well below typical US concentrations.

Sulfur Dioxide: Same as sodium sulfite: sulfite-sensitive individuals (1% of population, 5% of asthmatics) can experience severe reactions. SO2 in wine has been identified as a contributor to wine-induced headache and asthmatic episodes. Occupational exposure to SO2 gas causes respiratory irritation, bronchospasm, and lung damage at higher concentrations — relevant to workers in winemaking and food processing but not typical dietary exposure levels.

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