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Answer: Yes — Titanium Dioxide is banned in 2 countries/regions including European Union (banned as food additive E171 since August 2022), France (banned nationally in 2020, first EU country to do so). The FDA still allows it in US food. Commonly found in: Skittles (US formulation), Starburst shells, M&Ms (white coating).
TL;DR: Titanium Dioxide is banned in the EU but allowed in the US (food additives).
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Also called TiO2. (E171)
Other names: TiO2, E171, CI 77891
| EU status | Banned |
|---|---|
| US status | Allowed |
| Risk level | — |
| Where it shows up | Skittles (US formulation), Starburst shells, M&Ms (white coating), Many chewing gum brands, Salad dressings, Non-dairy coffee creamers |
Titanium dioxide (TiO2) is a naturally occurring white mineral used as a food colorant, whitening agent, and opacity enhancer. In food applications, it exists as nano-sized and micro-sized particles. It is one of the most widely produced industrial minerals globally, used in paints, plastics, sunscreens, and food products.
In food, titanium dioxide provides intense white color and opacity to candies, chewing gum, salad dressings, coffee creamers, and cake frostings. It gives products a bright, appealing white appearance. In sunscreens and cosmetics, it serves as a UV filter. Its historically perceived inertness made it considered safe for decades.
The EU banned titanium dioxide as a food additive in 2022 following EFSA's landmark 2021 safety assessment (EFSA Journal 2021;19(5):6585), which concluded that titanium dioxide 'can no longer be considered safe as a food additive.' The primary concern is genotoxicity from nanoparticles: EFSA determined it was impossible to rule out the risk of DNA damage (genotoxicity) from TiO2 nanoparticles at typical food use exposure levels. In vitro studies have demonstrated that TiO2 nanoparticles cause DNA strand breaks in intestinal epithelial cells and induce oxidative stress. A 2019 study in Nature Communications found TiO2 nanoparticles could disrupt gut microbiome balance and intestinal barrier function in mice models. Multiple studies have suggested effects on gut permeability and immune function. IARC classifies titanium dioxide as Group 2B (possible human carcinogen) for inhalation exposure in occupational settings — primarily relevant to workers handling TiO2 dust, based on rat lung cancer studies. While inhalation and oral exposure are different routes, EFSA determined that the genotoxicity concerns from nanoparticles applied to oral food use as well. Following the EU ban, California attempted to pass legislation banning TiO2 in candy (along with other additives) in 2022. The bill was signed in modified form. Mars reformulated EU Skittles to remove TiO2. The US FDA has not announced specific action on food-grade TiO2 as of 2025, though USRTK and other organizations are calling for a US ban.
For educational use only. This page summarizes the regulatory status of Titanium Dioxidewith citations to the primary sources below. It is not medical advice. Regulatory status is not the same as a proven health effect — read the cited sources for their exact wording, and consult a doctor for decisions about your or your family's health.
Calcium carbonate provides whiteness and opacity in confections as a TiO2 alternative. Calcium sulfate, starch-based whiteners, and reformulated coatings without white pigment are other options. European manufacturers successfully reformulated after the 2022 EU ban. Some manufacturers eliminated white coatings entirely.
Yes. EU banned TiO2 as a food additive (E171) in August 2022 after EFSA concluded in 2021 its safety could no longer be guaranteed due to genotoxicity concerns from nanoparticles. France had already banned it nationally in 2020.
TiO2 was historically used in Skittles' white coating. Mars reformulated EU Skittles to remove it after the 2022 EU ban. The US version of Skittles may still contain TiO2. This difference was widely publicized and contributed to California's legislative efforts.
FDA currently considers it safe at food use levels. EFSA's 2021 assessment — the most comprehensive review — concluded it can no longer be considered safe as a food additive due to inability to rule out nanoparticle DNA damage. Scientific consensus appears to be shifting toward precaution.
In food, TiO2 is a white colorant and opacity agent used in candies, gum, dressings, creamers, and cake frostings. Particles range from nano to micro scale.
IARC Group 2B for inhalation occupational exposure (rat lung cancer studies). EFSA's food ban concerns focus on genotoxicity from nanoparticles via oral exposure. Different mechanisms, both concerning.
Animal studies suggest TiO2 nanoparticles may disrupt gut microbiome and intestinal barrier function. 2019 Nature Communications study documented these effects. This contributed to EFSA's 2021 safety reassessment.
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Calcium carbonate, reformulated coatings without white pigment, and elimination of the white outer shell layer. Manufacturers have successfully reformulated. Tic Tac, Skittles (EU), and other major brands have removed TiO2.
FDA approved TiO2 as a sunscreen active ingredient. Current evidence suggests minimal skin penetration in healthy skin for lotion forms. Spray sunscreens with TiO2 nanoparticles raise inhalation concerns similar to occupational exposure.
Audited products that don't contain Titanium Dioxide.
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