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Alpha-isomethyl ionone is permitted by the US FDA. Several countries restrict, warning-label, or have reviewed it for safety concerns. The US has more lenient additive rules than the EU, UK, Canada, and Japan, which is why this ingredient remains widely used here.
An EU-listed fragrance allergen requiring declaration.
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See the full Alpha-isomethyl ionone deep-dive page for regulatory citations, products that contain it, and verified clean swaps.