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Sodium Cocoyl Isethionate is permitted by the US FDA. Several countries restrict, warning-label, or have reviewed it for safety concerns. The US has more lenient additive rules than the EU, UK, Canada, and Japan, which is why this ingredient remains widely used here.
Sodium cocoyl isethionate has an excellent safety record. It is one of the surfactants recommended by the National Eczema Association for sensitive and atopic skin. No carcinogenic, mutagenic, or endocrine-disrupting effects are known. Potential contact sensitization is extremely rare. It performs well at physiological pH, minimizing skin barrier disruption.
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