Is Polyaminopropyl biguanide Safe During Pregnancy?
The facts: Polyaminopropyl biguanide is restricted in European Union, though the FDA still allows it in the US. We can't tell you whether it's safe for your pregnancy — that's a conversation for your OB-GYN or midwife. What we can do is show you the regulatory facts and flag Polyaminopropyl biguanide on any product's label so you can decide with your provider. Commonly found in: wipes, sprays, lotion.
TL;DR: Polyaminopropyl biguanide is restricted in the EU and allowed in the US. Here's what to know if you're pregnant.
Polyaminopropyl biguanide: regulatory status at a glance
| EU status | Restricted |
|---|---|
| US status | Allowed |
| Risk level (regulatory) | medium |
| Where it shows up | wipes, sprays, lotion |
What is Polyaminopropyl biguanide?
Polyaminopropyl biguanide (Polyaminopropyl Biguanide) is a preservative (PHMB).
Why is Polyaminopropyl biguanide used in personal-care products?
It is used for its preservative, coloring, fragrance, solvent or texture-enhancing function.
What regulators have flagged about Polyaminopropyl biguanide
A possible carcinogen by inhalation; the EU restricts it.
For educational use only. This page summarizes the regulatory status of Polyaminopropyl biguanide with citations to the primary sources below. It is not medical advice and is not pregnancy-specific medical guidance. Consult your OB-GYN or midwife for decisions about your pregnancy.
Pregnancy-conscious swaps free from Polyaminopropyl biguanide →
Audited products that don't contain Polyaminopropyl biguanide.
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Polyaminopropyl biguanide and pregnancy: common questions
Is Polyaminopropyl biguanide banned anywhere?
Yes. Polyaminopropyl biguanide is restricted in European Union. The FDA still allows it in the US.
Should I avoid Polyaminopropyl biguanide during pregnancy?
That's a decision for you and your OB-GYN or midwife — we don't give medical advice. What we can tell you is the regulatory status above. Many people choose to limit additives during pregnancy out of caution; bring this page and its sources to your next appointment.
What products contain Polyaminopropyl biguanide?
Commonly found in wipes, sprays, lotion. Scan any product's barcode to check its label for Polyaminopropyl biguanide.
What can I use instead of Polyaminopropyl biguanide?
Choose EU-compliant or 'free-from' formulations and read the INCI list. BannedPantry flags this ingredient and suggests safer swaps. See the pregnancy-conscious swaps below.
Scan any product's barcode and instantly see if it contains Polyaminopropyl biguanide or other ingredients restricted overseas.
Scan a product free →Other ingredients to check during pregnancy
Sources
- EU Cosmetics Regulation Annex II (prohibited substances) — EU Cosmetics Regulation 1223/2009
- EU-banned cosmetics ingredients and US impact — RegASK
- Chemicals in cosmetics — CHEM Trust
Our scores are never influenced by brands. Last updated 6/11/2026.