Is Propylene Glycol Safe During Pregnancy?
The facts: Propylene Glycol is restricted in European Union (not permitted as a direct food additive in most food applications; only permitted as a carrier solvent for specific additives at low levels), though the FDA still allows it in the US. We can't tell you whether it's safe for your pregnancy — that's a conversation for your OB-GYN or midwife. What we can do is show you the regulatory facts and flag Propylene Glycol on any product's label so you can decide with your provider. Commonly found in: Artificial flavors (as solvent), Some salad dressings, Certain baked goods and icings.
TL;DR: Propylene Glycol is restricted in the EU and allowed in the US. Here's what to know if you're pregnant.
Propylene Glycol: regulatory status at a glance
| EU status | Restricted |
|---|---|
| US status | Allowed |
| Risk level (regulatory) | — |
| Where it shows up | Artificial flavors (as solvent), Some salad dressings, Certain baked goods and icings, Some food colorings (as vehicle), Various cosmetics and skincare products, Electronic cigarette liquids (not food) |
What is Propylene Glycol?
Propylene glycol is a synthetic organic compound used as a humectant, solvent, and emulsifier in food, pharmaceuticals, cosmetics, and industrial applications. It is produced from propylene oxide (derived from petroleum). Its chemical formula is C3H8O2.
Why is Propylene Glycol used in food?
Propylene glycol maintains moisture in food (humectant), acts as a solvent for food flavors and coloring, and preserves food texture. Used in artificial flavorings, salad dressings, baked goods, packaged icings, and as a vehicle for food dyes. In cosmetics, it is used as a moisturizer and solvent.
What regulators have flagged about Propylene Glycol
Propylene glycol is generally considered safe by the FDA and is metabolized by the liver to lactic acid and pyruvate (normal metabolites). However, at high doses — particularly from intravenous pharmaceutical formulations — propylene glycol can accumulate and cause lactic acidosis, kidney toxicity, and CNS effects. These effects are seen in critically ill patients receiving high-dose PG-containing intravenous medications, not from food consumption. In children and people with impaired liver or kidney function, PG accumulation may occur at lower doses than in healthy adults. Animal studies have found reproductive and developmental effects at high doses. EFSA's 2018 re-evaluation found no concerns at typical food use levels but noted the EU limits PG use as a direct food additive, using it only as a carrier solvent for permitted additives.
For educational use only. This page summarizes the regulatory status of Propylene Glycol with citations to the primary sources below. It is not medical advice and is not pregnancy-specific medical guidance. Consult your OB-GYN or midwife for decisions about your pregnancy.
Pregnancy-conscious swaps free from Propylene Glycol →
Audited products that don't contain Propylene Glycol.
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Propylene Glycol and pregnancy: common questions
Is Propylene Glycol banned anywhere?
Yes. Propylene Glycol is restricted in European Union (not permitted as a direct food additive in most food applications; only permitted as a carrier solvent for specific additives at low levels). The FDA still allows it in the US.
Should I avoid Propylene Glycol during pregnancy?
That's a decision for you and your OB-GYN or midwife — we don't give medical advice. What we can tell you is the regulatory status above. Many people choose to limit additives during pregnancy out of caution; bring this page and its sources to your next appointment.
What foods contain Propylene Glycol?
Commonly found in Artificial flavors (as solvent), Some salad dressings, Certain baked goods and icings, Some food colorings (as vehicle), Various cosmetics and skincare products, Electronic cigarette liquids (not food). Scan any product's barcode to check its label for Propylene Glycol.
What can I use instead of Propylene Glycol?
Vegetable glycerin (glycerol) is a natural alternative to propylene glycol as a humectant and solvent. Water, alcohol, and plant-based solvents can substitute in many applications. Natural flavor carriers and essential oils replace PG in fl See the pregnancy-conscious swaps below.
Scan any product's barcode and instantly see if it contains Propylene Glycol or other ingredients restricted overseas.
Scan a product free →Other ingredients to check during pregnancy
Sources
Our scores are never influenced by brands. Last updated 6/10/2026.