Is Sodium PCA Banned? EU vs US Status, Risks & Where It Hides
TL;DR: Sodium PCA is allowed in the EU but allowed in the US (humectant).
INCI name SODIUM PCA. Also called NaPCA. CAS 28874-51-3.
Other names: Sodium L-Pyroglutamate, NaPCA
Is Sodium PCA banned in the EU?
| EU status | Allowed |
|---|---|
| US status | Allowed |
| Risk level | low |
| Where it shows up | Neutrogena Hydro Boost range, The Ordinary Natural Moisturizing Factors + HA, Paula's Choice Moisturizer formulas |
| CAS number | 28874-51-3 |
What is Sodium PCA?
Sodium PCA (sodium L-pyroglutamate) is the sodium salt of pyroglutamic acid, a naturally occurring component of the skin's Natural Moisturizing Factor (NMF). It is an exceptionally effective humectant with a higher water-binding capacity than glycerin.
Why is Sodium PCA used in personal-care products?
Used to attract and retain moisture in the skin. As a component of natural skin NMF, it is highly biocompatible and particularly effective at skin hydration without occlusion.
Is Sodium PCA dangerous? Documented risks
Sodium PCA is one of the safest and most skin-compatible humectants available. It is endogenous to healthy skin and has no known adverse effects. The CIR has confirmed its safety. It is non-irritating, non-sensitizing, non-comedogenic, and safe for all skin types.
Products that may contain Sodium PCA
- CeraVe Renewing SA CleanserCeraVe
- Native Body Wash Sea Salt & CedarNative
- CeraVe Daily Moisturizing LotionCeraVe
- CeraVe Moisturizing CreamCeraVe
- CeraVe Hydrating Facial CleanserCeraVe
- CeraVe Foaming Facial CleanserCeraVe
- CeraVe PM Facial Moisturizing LotionCeraVe
- The Ordinary Natural Moisturizing Factors + HAThe Ordinary
How to avoid Sodium PCA: safer alternatives
Glycerin or hyaluronic acid for alternative humectant strategies.
Frequently asked questions about Sodium PCA
Is sodium PCA a natural ingredient?
It is identical to a component found naturally in healthy skin (Natural Moisturizing Factor). Cosmetic sodium PCA is synthesized but mirrors the body's own hydration molecules.
How does sodium PCA compare to hyaluronic acid?
Both are excellent humectants. Sodium PCA has a smaller molecule and can penetrate slightly better; hyaluronic acid forms a stronger surface film. Many formulas combine both.
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Sources
- CIR Safety Assessment of PCA and related compounds — Cosmetic Ingredient Review
- EWG Skin Deep: Sodium PCA — Environmental Working Group
Our scores are never influenced by brands. Last updated 6/11/2026.